| abstract |
The invention discloses an application of astragalus polysaccharides combined with mesenchymal stem cells in the preparation of medicines for treating advanced liver cirrhosis. The components of traditional Chinese medicine preparations for advanced liver cirrhosis are astragalus total polysaccharides 10‑100 parts, astragalus total saponins 10‑80 parts, salvia phenolic acids 3‑50 parts, total tanshinone 5‑30 parts, ginseng polysaccharides 5‑30 parts, ginseng total saponins 5‑30 parts, Ganoderma polysaccharide 5‑30 parts. The mesenchymal stem cells of the present invention can repair damaged stem cells through directional differentiation and paracrine cytokines; total astragalus saponins and astragalus total polysaccharides have the effect of enhancing and regulating the immune system; It also has obvious hepatoprotective effect; the organic combination of advanced techniques such as water extraction and alcohol precipitation, high-speed centrifugation, macroporous resin adsorption separation, low-temperature concentration, spray drying, etc., makes the extract of the prepared medicine have many active ingredients and high purity , good efficacy. |