| abstract |
The present invention relates to a substituted pyrazolo [1,5-a ] as Trk kinase inhibitors]Pyrimidine compounds, or pharmaceutically acceptable salts, pharmaceutical compositions and uses thereof. The pyrazolo [1, 5-a) with the structure of the general formula (I)]The pyrimidine derivative has good Trk family protein tyrosine kinase inhibition activity and metabolic stability. |