http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110294709-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-04 |
| filingDate | 2019-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110294709-B |
| titleOfInvention | 1,3- [2H,4H ] -isoquinoline dione derivative and preparation method and application thereof |
| abstract | The invention belongs to the field of biomedicine, and particularly relates to 1,3- [2H,4H ]]-isoquinolinedione derivatives, their preparation and use. The 1,3- [2H,4H]The structural general formula of the isoquinoline diketone derivative is shown as a general formula (1), wherein, R is H, F, Cl, Br, -CH 3 、‑OCH 3 One or two of methylthio, ethyl, amino and acetyl; r 1 The radicals being H, F, Cl, Br, -CH 3 、‑OCH 3 One or two of methylthio, ethyl, amino and acetyl; r 2 The radical being-CH 3 Ethyl, acetyl, benzyl, propenyl and phenyl. 1,3- [2H,4H ] of the invention]The-isoquinoline dione derivative has a good inhibition effect on an acinetobacter baumannii quorum sensing system, the harm of the acinetobacter baumannii is greatly reduced, the preparation method is simple, and the prepared product can be used as a biomembrane inhibitor to be applied to preparation of anti-infection chiral drugs. |
| priorityDate | 2019-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.