http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110286162-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-062 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-027 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 |
| filingDate | 2019-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110286162-B |
| titleOfInvention | A kind of determination method of dissolution rate of pharmaceutical preparation containing paracetamol, dextromethorphan hydrobromide and doxylamine succinate |
| abstract | The invention discloses a method for determining the dissolution rate of a pharmaceutical preparation containing paracetamol, dextromethorphan hydrobromide and doxylamine succinate. The steps are as follows: (1) The pharmaceutical preparations of dextromethorphan and doxylamine succinate are added to the dissolution medium for dissolution treatment, sampling and filtration to obtain a dissolution liquid; (2) Detecting paracetamol, dextromethorphan hydrobromide and succinate in the dissolution liquid content of doxylamine acid; (3) determining the dissolution rate of the pharmaceutical preparation according to the detection result of step (2). The invention can effectively simulate the dissolution behavior in vivo in vitro, determine the dissolution rate of soft capsules containing paracetamol, dextromethorphan hydrobromide and doxylamine succinate, and provide technical support for drug research and development and quality control . The invention can simultaneously measure the dissolution results of the three substances under the same condition, greatly saves the detection time and the detection cost, and has good accuracy and reproducibility. |
| priorityDate | 2019-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.