| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_531a4e7d67d9993d918bb6a4fc905235 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-32022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-32322
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10021
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-32334 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-41 |
| filingDate |
2019-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c0516b8ce9640886c02d578d144ee31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c4b1e466c457437056a7d8efb6d9d4c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5840534cf05348fe4ee2106953e4a01c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25f08277884ac7f75a9d73b6b027ba9d |
| publicationDate |
2019-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-110283795-A |
| titleOfInvention |
Recombinant Adenovirus Displaying Neutralizing Epitopes of EV71 Virus and CVA16 Virus Simultaneously |
| abstract |
The present invention provides a recombinant adenovirus capable of simultaneously displaying EV71 virus and CVA16 virus neutralizing epitope, wherein the hexon HVR1 region of the recombinant adenovirus is inserted with EV71 virus SP70 neutralizing antigen epitope gene, said The hexon HVR2 region of the recombinant adenovirus is inserted with the CVA16 virus PEP55 neutralizing antigen epitope gene. The invention also provides a preparation method of the recombinant adenovirus. The recombinant adenovirus of the invention can induce the body to produce effective neutralizing antibodies to the EV71 virus and the CVA16 virus, thereby preventing hand, foot and mouth disease caused by the EV71 virus and the CVA16 virus. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111235118-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111235118-B |
| priorityDate |
2019-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |