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filingDate 2019-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2019-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110283327-A
titleOfInvention A kind of conjugated polymer nanoparticle fluorescent probe and its application
abstract The invention provides a conjugated polymer nanoparticle fluorescent probe and its application. The invention prepares the conjugated polymer into the conjugated polymer nanoparticle through a nano-precipitation method, and performs carboxylation treatment on the conjugated polymer nanoparticle. According to the test, Fe 3+ can agglomerate the carboxylated conjugated polymer nanoparticles (CPNs‑PBOC‑COOH) to form CPNs‑PBOC‑COOH‑Fe 3+ , so that the fluorescence of CPNs‑PBOC‑COOH can pass through Fe 3 The fluorescence resonance energy transfer effect of + is effectively quenched, that is, an ideal fluorescent probe is obtained. Experiments have proved that this fluorescent probe based on conjugated polymer nanoparticles has high selectivity and sensitive response to AA. The concentration of detected AA is linear in the range of 0.57-10.26 μM, and the limit of detection (LOD) value is 76.3nM, which has good practical application value.
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