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filingDate 2019-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_094063724e526b4f415486cd31cc9975
publicationDate 2019-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110279781-A
titleOfInvention A kind of leaves of pulse plants summer capsule with antitumor action
abstract The invention discloses a kind of leaves of pulse plants summer capsule with antitumor action, including following raw materials: Herba Epimedii, Prunella vulgaris, Sweet Broomwort Herb and wart handle rub taro, prepared by following methods: raw material extracts: take 2.6-3.5 part wart handle in above-mentioned formula rub crush after taro clean dry for 80 mesh fine powders it is spare, water is added in remaining raw material, decompression is extracted three times under the conditions of 0.1atm atmospheric pressure is heated to 60 DEG C, and filtrate is taken to be concentrated to give thick paste;Take that wart handle rubs taro fine powder and thick paste prepares leaves of pulse plants summer dried cream powder;The ethanol solution for being 50% using concentration as wetting agent, be prepared into the leaves of pulse plants summer it is particles filled enter capsulae vacuus in, obtain the leaves of pulse plants summer capsule that every gram of leaves of pulse plants summer particle is equivalent to 12.5 grams of crude drug amount.For the present invention by suppression cancer test in vitro and the test of internal transplanted tumor in nude mice, demonstrating leaves of pulse plants summer capsule has inhibitory activity to NCI-H460 cell in vivo and in vitro, and can induce cell apoptosis.Its mechanism of action may improve TNF- with removing free radical α Content, inhibits IL-6 secretion, and the expression for increasing Bax, Caspase-3 gene is related.
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type http://data.epo.org/linked-data/def/patent/Publication

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