http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110279697-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-357 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-357 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 |
| filingDate | 2019-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110279697-B |
| titleOfInvention | Application of iron death inducer in medicine for treating or relieving allergic airway inflammation |
| abstract | The invention provides an application of an iron death inducer in a medicament for treating or relieving allergic airway inflammation, wherein the iron death inducer realizes the treatment or the relief of the allergic airway inflammation by targeted induction of eosinophilic iron death. The invention introduces the concept of eosinophilic iron death in the treatment of allergic airway diseases for the first time. We found that iron death inducers can induce iron death in human and mouse eosinophils in vitro; through constructing an animal model, the iron death inducer can obviously relieve allergic airway inflammation of mice; in addition, the iron death inducer artesunate has a synergistic regulation effect on allergic airway inflammation protection and glucocorticoid, and has great research significance for reducing the dosage of hormone and relieving systemic side effects caused by the hormone. The invention provides a new idea and a new target point for clinically developing novel medicaments for treating allergic airway diseases and even systemic eosinophil-related diseases in the future. |
| priorityDate | 2019-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.