http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110279654-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-616 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-616 |
| filingDate | 2019-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2023-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2023-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110279654-B |
| titleOfInvention | Sustained-release aspirin liposome hydrogel, preparation method and application thereof in preparation of medicine for treating recurrent lumbar disc herniation |
| abstract | The invention discloses a slow-release aspirin liposome hydrogel, a preparation method and its application in the preparation of medicines for treating recurrent lumbar disc herniation after intervertebral discectomy. The slow-release aspirin liposome hydrogel comprises aspirin, Liposome and gelatin methacryloyl hydrogel; and through the observation of the structural and mechanical characteristics of the sustained-release aspirin liposome hydrogel, the effect of materials on the inflammation of nucleus pulposus cells in vitro, and the formation of annulus fibrosus defects in rabbits in vivo Model test to confirm the effect and possible mechanism of slow-release aspirin liposome hydrogel in the treatment of intervertebral disc degeneration caused by annular fibrosus defect, and to confirm the filling, maintenance of mechanical stability and local inflammation of ASP‑Lip+GelMA in some annular fibrosus defects in rabbits demonstrated superior performance in terms of control, providing a new therapeutic perspective for the prevention of recurrent lumbar disc herniation after partial discectomy. |
| priorityDate | 2019-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 205.