| abstract |
The invention discloses a Vc liposome and its preparation method and application. A preparation method of Vc liposome, the raw materials of the film material are dissolved in an appropriate volume of chloroform, the chloroform is removed by evaporation under reduced pressure, a lipid film is formed in a round-bottomed flask, and after adding a Vc aqueous solution for hydration and ice bath ultrasonication, Filter membranes with pore diameters of 0.45 μm and 0.22 μm in turn to obtain liposomes with a diameter of about 100-160 nm and a potential of 30-40 mV; wherein the mass-volume ratio of the membrane material in the Vc aqueous solution is 2.5-3.0 mg/mL; The membrane material described is composed of lecithin, cholesterol, octadecylamine and vitamin E. Using this cationic liposome to transport Vc solves the defects that Vc is not easy to preserve, easy to oxidatively degenerate and has poor transdermal effect, greatly improves the transdermal effect of vitamin C, makes it more effectively transferred into cells, and can play a better role. It has great antioxidant effect and can be added to various cosmetics as a cosmetic raw material. |