http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110272370-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aaadcd534c1edeab62f85ec7991cb759 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-10 |
| filingDate | 2019-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bebd66feb81bb5b3fbb2e124c1d999bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b2d76300ef655cd7a0226a17d3b340f |
| publicationDate | 2019-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110272370-A |
| titleOfInvention | A kind of synthetic method of trifluoromethyl-substituted 3,3'-bis(2-phenylindolyl)methane compound |
| abstract | The invention belongs to the technical field of chemical synthesis of organic fluorine, and relates to a method for synthesizing trifluoromethyl-substituted 3,3'-bis(2-phenylindolyl)methane compounds, using 2-phenylindole as a base compound, trifluoroacetyl hydrazide as fluoroalkyl source, under the action of Cu catalyst, di-tert-butyl peroxide DTBP or dicumyl peroxide as oxidant, potassium tert-butoxide, lithium tert-butoxide or potassium methoxide as oxidant Under the condition of alkali, magnesium trifluoromethanesulfonate or silver trifluoromethanesulfonate as Lewis acid, and 1,2-dichloroethane DCE as solvent, one-step synthesis of trifluoromethyl-substituted 3,3'-bis(2 -phenylindolyl)methane compound. The synthetic method has the advantages of simple operation, cheap and readily available raw materials, and diversified products. |
| priorityDate | 2019-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 121.