http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110272351-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c8474b218406eaa8df0be62192770e6f |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-02 |
filingDate | 2019-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb8f0479453abf1c03abe57dd960a630 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_278254f58ded605f73230b5798718c10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b1fc5a50e380ebbf39b703c9ea536d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7dab93f77c95e6f04dc4c6e95d2f3758 |
publicationDate | 2019-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110272351-A |
titleOfInvention | A kind of synthetic method of diclofenac |
abstract | The invention provides a synthesis method of diclofenac, which belongs to the technical field of drug synthesis; the specific reaction steps of the synthesis method of the invention are as follows: step 1): compound (a) is reacted in the presence of methanol/sodium methoxide to obtain compound (b); Step 2): compound (b) reacts with compound (c) in the presence of a base to obtain compound (d); step 3): compound (d) reacts with compound (e) in an organic solvent under the action of a catalyst, The compound (f) is obtained; the raw materials of the method are easy to obtain, the operation is simple, the yield is high, the cost is low, the three wastes are less, the safety is high, and it is suitable for industrial production. |
priorityDate | 2019-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.