http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110269858-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 |
filingDate | 2019-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110269858-B |
titleOfInvention | Twin medicine for treating ischemic stroke and preparation method thereof |
abstract | The invention belongs to the technical field of medicinal chemistry, in particular to a twin drug for treating ischemic stroke and a preparation method thereof, wherein the twin drug is obtained by splicing 2-bromomethyl-3, 5, 6-trimethyl pyrazine and scutellarin aglycone in the same chemical entity through ether bonds or splicing carbon-nitrogen bonds in L-amino acid salt; the invention exerts the synergistic effect through a twin drug design strategy; the twin medicine of the invention has good free radical scavenging activity and thrombolytic activity, and is a novel medicine for treating cerebral arterial thrombosis. |
priorityDate | 2019-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 206.