http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110257337-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-15043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867 |
| filingDate | 2018-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110257337-B |
| titleOfInvention | An FTL knockdown human prostate cancer cell line |
| abstract | The invention provides a lentivirus-infected human prostate cancer cell line (PC-3) to knock out endogenous genes, and successfully establish a stable screening cell line. Specifically, FTL-shRNA lentivirus was used to infect PC-3 cell line to silence FTL (ferritin light chain) expression, and FTL-knockdown PC-3 cell line was successfully established. The present invention confirms through research that FTL knockdown PC-3 cell line can stably silence FTL expression and passage. Compared with the negative control, the expression level of FTL protein in the PC-3 cell line after knockdown of FTL was significantly decreased, and the cell proliferation and migration ability were significantly enhanced. |
| priorityDate | 2018-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 123.