http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110257051-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1466 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-145 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y20-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-883 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y20-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-04 |
| filingDate | 2019-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110257051-B |
| titleOfInvention | Preparation method of DNA functionalized quantum dots based on click chemistry and application of DNA functionalized quantum dots in biomarker and detection |
| abstract | The invention discloses a preparation method of a DNA functionalized quantum dot based on click chemistry and application of the DNA functionalized quantum dot in biological labeling and detection. Relates to the field of nano materials and biomedical analytical chemistry. The preparation method comprises the step of adding DNA with one end modified by azide or diphenyl cyclooctyne and the other end modified by thiophosphate into the quantum dot synthesis process to serve as a co-stabilizer of the quantum dot, so as to obtain the azide or diphenyl cyclooctyne modified DNA functional quantum dot labeling reagent. The quantum dot labeling reagent can be used for efficiently labeling protease and cancer cells, and can be used for biological detection and imaging analysis. By combining the DNA hybridization principle, the labeling reagent also has important application value in the aspects of nano material self-assembly and the like. Meanwhile, compared with other fluorescence labeling reagents based on click chemistry, the preparation method of the labeling reagent is simple, does not need any chemical modification, is easy to purify and has excellent fluorescence performance. |
| priorityDate | 2019-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 99.