| abstract |
The invention discloses a purine compound serving as a Trk kinase inhibitor, belonging to the field of chemical medicine. The purine compound is shown as a general formula (I), has good Trk family protein tyrosine kinase inhibitory activity, can be used for treating cancer, pain, inflammation, neurodegenerative diseases, trypanosoma cruzi infection or osteolytic diseases of mammals, and has wide application prospect. |