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filingDate 2019-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110237311-B
titleOfInvention Polydopamine-exosome core-shell structure nanoparticle, intravascular stent material prepared by modifying same and application of intravascular stent material
abstract The invention discloses a polydopamine-exosome core-shell structure nanoparticle, a vascular stent material prepared by modifying the same and application of the polydopamine-exosome core-shell structure nanoparticle, and belongs to the technical field of surface modification of cardiovascular stent materials, wherein the preparation process of the nanoparticle is as follows: dissolving dopamine hydrochloride in a Tris buffer solution, adding exosome suspension with the concentration of 25 mug/mug-100 mug/mug into the dopamine-Tris buffer solution according to the volume ratio of 1:5-100, carrying out reaction for 15-6 h in a shaking table at 4-60 ℃ in a dark place for 40-140 circles/minute, centrifuging, removing supernatant, retaining the deposited particle suspension, adding the deposited particle suspension into the dopamine-Tris buffer solution according to the volume ratio of 1:5-100, carrying out reaction for 15-6 h in the shaking table at 4-60 ℃ in a dark place for 40-140 circles/minute, centrifuging, removing the supernatant, and obtaining the solid which is the poly-dopamine-exosome core-shell structure nanoparticle.
priorityDate 2019-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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