| abstract |
The present invention provides compounds of formula I, and pharmaceutically acceptable salts thereof, wherein the variables R 1 , R 2 , R 3 , R 4 , R 9 , X, m and n are as defined herein; methods for preparing these compounds or salts; for preparing these compounds or intermediates of salts; and compositions containing these compounds or salts, and uses thereof, for the treatment of kappa opioid (κ-opioid)-related disorders, including, for example, neurological disorders, or psychiatric disorders, such as neurocognitive disorders , substance use disorders, depression, anxiety disorders, trauma and stressor-related disorders, and eating and eating disorders. |