http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110232978-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca46be4e68fa1f5a8b2ef4ab654c490a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H70-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B25-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B25-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16H70-40 |
| filingDate | 2019-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb6256f346272f9e6f7626368ee5f315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7048353b1cbfea7b77ba731ff51670d9 |
| publicationDate | 2019-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110232978-A |
| titleOfInvention | Multidimensional network-based drug prediction method for cancer cell lines |
| abstract | The invention discloses a method for predicting cancer cell line therapeutic drugs based on a multi-dimensional network, which mainly solves the problem of low accuracy rate of prediction results of cancer cell line therapeutic drugs in the prior art. The scheme is: download the data of n cancer cell lines, and construct the cancer cell line similarity network; download the data of m drugs, and construct the drug similarity network; in the cancer cell line similarity network, use the diffusion component analysis algorithm to calculate The low-dimensional eigenvector matrix of n cancer cell lines; in the drug similarity network, the low-dimensional eigenvector matrix of m drugs is calculated by using the diffusion component analysis algorithm; the logistic regression model of drug response is obtained; the calculation of drugs and cancer cell lines The scores of the sensitivity relationship between them are used to judge whether the drug has a therapeutic effect on the cancer cell line by the score of the sensitivity relationship. The invention improves the accuracy rate of the prediction result of the cancer cell line therapeutic drug, and can be used for the prediction experiment of the cancer's response to the drug. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112768089-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114255886-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112289389-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112635080-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110867254-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022214036-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115206421-A |
| priorityDate | 2019-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.