| abstract |
The invention discloses a plasma marker combination for early diagnosis or prognosis prediction of colorectal cancer. Specifically, the present invention obtains miRNAs significantly abnormally expressed in colorectal cancer plasma, namely miR-224-5p, miR-301a-3p, miR-145-5p, miR-193b-3p and miR-1183. The present invention finds that the plasma miRNA combination can be used as a marker for early diagnosis or prognosis of colorectal cancer by studying the expression differences of these plasma miRNAs in patients with colorectal cancer at various stages, patients with colorectal adenoma and healthy people. |