http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110229368-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2367-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2477-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2393-02 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K23-018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K23-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J7-0427 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L93-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K23-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L77-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L67-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-14 |
filingDate | 2019-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110229368-B |
titleOfInvention | Janus particles with biocompatibility and preparation method thereof |
abstract | The invention discloses a Janus particle with biocompatibility and a preparation method thereof. The present invention adopts biocompatible materials, dissolves shellac and polylactic acid materials in a common good solvent, and then quickly injects the mixed solution into an aqueous solution containing a surfactant at a certain temperature, based on the mechanism of co-precipitation and phase separation , to obtain shellac-polylactic acid Janus nanoparticles whose one end is shellac and the other end is polylactic acid. By adjusting the concentration of shellac and polylactic acid in the good solvent, the size of Janus nanoparticles can be regulated; by adjusting the ratio of shellac and polylactic acid in the good solvent, the hemisphere of shellac and polylactic acid in Janus nanoparticles can be regulated. Proportion. Then, through the interaction of positive and negative charges, biocompatible polylysine is modified on the surface of the shellac hemisphere to improve the hydrophilicity of the shellac hemisphere. The biocompatible Janus nanoparticle of the present invention has amphiphilicity, and as a particle surfactant, it can well stabilize the emulsion of oil in water. |
priorityDate | 2019-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.