http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110229156-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b63eecd60f32153abcb6478d3930dc3a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4866 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 |
| filingDate | 2018-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_296aa3baffe3b1b169c9ad3858e9796d |
| publicationDate | 2019-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110229156-A |
| titleOfInvention | Ai Wei replaces the new synthesis route and its maleate dihydrate of Buddhist nun |
| abstract | The invention discloses a kind of new synthesis process that Ai Wei replaces Buddhist nun, and with the chloro- 4- of 2- (3- nitro-phenoxy) -7 hydrogen-(pyrrolo- [2,3-d] pyrimidine) -1- methyl- tert butyrate for starting material, reaction route is short, and gross production rate is high；Deprotection is more easier, and post-processing is simple, has important application value in large-scale production.The invention further relates to maleate dihydrate and its preferred crystal forms, have excellent powder characteristics, are particularly conducive to solid pharmaceutical preparation processing, are especially formed into capsule.Finally, the good fluidity of content, release reaches standards of pharmacopoeia the invention also discloses using maleate dihydrate as the capsule of active constituent. |
| priorityDate | 2018-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.