abstract |
Embodiments of the present disclosure relate to systems, methods and devices for evaluating the secretion profile of single cells. In some embodiments, the device can be configured for analysis of substances expressed by biological cells and can include a first compressible base and be configured for removable sealing connection with the first base the second base. In some embodiments, after the second substrate is attached to the first substrate, an assembly is formed such that the open sides of the plurality of chambers are covered by the second substrate, and the plurality of A portion of each of the capture regions is exposed in each of the chambers. |