http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110204557-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-22 |
| filingDate | 2019-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110204557-B |
| titleOfInvention | Preparation method of cefamandole nafate derivative |
| abstract | The invention relates to a preparation method of a cefamandole nafate derivative, which comprises the steps of taking a compound 1 as an initial raw material, carrying out silanization protection, carrying out acylation reaction with D- (-) -O-formylmandelic acid acyl chloride, and then hydrolyzing and layering to obtain the cefamandole nafate derivative 1, wherein the structural formula of the compound 1 is as follows: the structural formula of the cefamandole nafate derivative 1 is as follows: said R 1 Is an alkyl group having 1 to 3 carbon atoms or an alkylhydroxy group having 1 to 3 carbon atoms. The preparation method can obtain the cefamandole nafate derivative with high yield, provides help for the related pharmaceutical research of cefamandole nafate, and provides an idea for synthesizing new cephalosporin compounds. |
| priorityDate | 2019-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.