http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110204510-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D285-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D285-24 |
| filingDate | 2019-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110204510-B |
| titleOfInvention | Method for synthesizing 1,2, 4-benzothiadiazine series compound in aqueous solution |
| abstract | The invention provides a preparation method of 1,2, 4-benzothiadiazine-1-oxide series compounds. The method adopts a one-pot reaction, uses commercially available 2-bromophenyl imino sulfone and aryl (alkyl) aldehyde as reaction substrates, uses stable, cheap and nontoxic copper oxide as a catalyst, uses water as a green and pollution-free solvent, and reacts for 12-15 hours at 80-100 ℃ in an air environment to synthesize the 1,2, 4-benzothiadiazine series compounds. The method takes water as a solvent, has no pollution to the environment basically, does not need alkali and inert gas protection, has no special requirements on reaction equipment, is simple and convenient to operate, adopts a one-pot reaction, and omits the operation of preparing and separating an intermediate, so the synthesis cost is extremely low. The product obtained by the method has excellent chemical selectivity, high production efficiency and wide substrate functional group compatibility, accords with the characteristic of green reaction, is suitable for large-scale preparation, has excellent industrial application prospect, and is an environment-friendly green chemical technology. |
| priorityDate | 2019-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.