http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110204468-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C331-14 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C331-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-70 |
filingDate | 2019-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110204468-B |
titleOfInvention | Asymmetric synthesis method of chiral alpha-thiocyano cyclic ketonic acid ester compound |
abstract | The invention discloses a method for synthesizing a chiral alpha-thiocyano cyclic ketonic acid ester compound shown as a formula (III): in the formula (I)The cyclic ketonic acid ester compound and the N-thiocyano phthalimide shown in the formula (II) are used as raw materials, under the action of a chiral catalyst, asymmetric thiocyanation reaction is carried out in an organic solvent until the reaction is complete, and after the reaction is finished, reaction liquid is subjected to post-treatment to obtain a corresponding product, namely the chiral alpha-thiocyano cyclic ketonic acid ester compound shown in the formula (III). The efficient synthesis method of the chiral alpha-thiocyano cyclic ketonic acid ester compound provided by the invention has the advantages of high yield, good enantioselectivity, wide range of reaction substrates, cheap and easily available reaction reagents and important application value. |
priorityDate | 2019-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 100.