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filingDate 2019-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110201167-B
titleOfInvention Preparation method of enzyme-loaded bismuth selenide nano-particles capable of releasing oxygen under illumination
abstract The invention discloses a preparation method of enzyme-loaded bismuth selenide nanoparticles releasing oxygen by illumination, relates to the field of synthesis of medicinal chemistry, and more particularly relates to a specific method for synthesizing hollow mesoporous bismuth selenide, loading enzyme-loaded bismuth selenide and perfluorocarbon and the like. The preparation method of the enzyme-loaded bismuth selenide nano-particle capable of releasing oxygen by illumination specifically comprises the following steps: (1) synthesizing bismuth selenide by a hydrothermal method, (2) synthesizing glucose oxidase on a hollow mesoporous bismuth selenide shell by an ion adsorption method, (3) filling perfluorocarbon into a bismuth selenide cavity by an ultrasonic method, and then filling oxygen. The obtained composite nano-drug delivery system has the advantages of accurate control of oxygen release, better photo-thermal property, good biocompatibility and the like.
priorityDate 2019-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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