| abstract |
The present invention relates to the preparation of ferric oxide-soybean polysaccharide-Ozagrel sodium composite nanomaterial, which makes soybean protein and soybean polysaccharide form a complex through high-pressure homogenization; dissolving divalent iron salt and ferric salt in deionized water , add dropwise to the above emulsion under rapid stirring, maintain a certain pH of the system, ultrasonically oscillate to make it fully dispersed, heat to a certain temperature, collect the solid phase, wash, freeze and dry to obtain proteoglycan-magnetic Nanoparticle complex; prepare sodium ozagrel into a solution of a certain concentration, mix it with the proteoglycan-magnetic nanoparticle complex according to a certain ratio, adjust the pH of the mixed system, ultrasonically disperse, and continue to stir. While the precipitate is formed, Due to the adsorption, the polysaccharide-magnetic particle complex and ozagrel sodium in the system co-precipitate to form composite nanoparticles with a size of 5nm-30nm. The invention has the advantages of safety, non-toxicity, strong magnetic response and good biological acceptability. |