http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110183459-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 |
filingDate | 2019-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110183459-B |
titleOfInvention | Alpha-mangostin derivative and preparation method and application thereof |
abstract | The invention provides an alpha-mangostin derivative (I), a preparation method thereof and application thereof in preparing neuroprotective drugs; the alpha-mangostin derivative is subjected to structural modification under the condition of keeping the basic structure of the alpha-mangostin unchanged; compared with alpha-mangostin, the water solubility of the modified new derivative is increased, and the bioavailability is improved; the alpha-mangostin derivative has good treatment effect on cerebrovascular diseases, and the activity of part of the derivative is stronger than that of ibuprofen which is a positive drug; therefore, the alpha-mangostin derivative has wide application prospect in the treatment of cerebrovascular diseases; |
priorityDate | 2019-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 85.