| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3ccb9e28f76f3f135717d1e723a452bb |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2019-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65c21a4fd92333db91d8b29208e8be67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82bafe29bb5a948bee2face7dc1490b6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b748cf2347792487a46b54515789ed3c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74514eea611818b3b3b4cf9c16957039
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9222cd865edd46e7cf30194636c8f571
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_943bc305d1368a885fe3e700ccf620da |
| publicationDate |
2019-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-110179986-A |
| titleOfInvention |
A kind of drug targets for treating colon cancer |
| abstract |
The invention discloses a kind of drug targets for treating colon cancer, which is PTBP3 and HIF-1 α.The present invention is using stabilization in vitro transfectional cell series or its xenograft formed as research object, it was demonstrated that inhibits HIF-1 α that can enhance the therapeutic effect for inhibiting PTBP3 to colon cancer by drug synergism.Two drug targets inhibit have obvious drug synergistic antitumor effect simultaneously, can be used as a kind for the treatment of method of novel colonic cancer. |
| priorityDate |
2019-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |