abstract |
The present invention, in various aspects and embodiments, relates to methods for treating Tie2-related vascular permeability by administering one or more collagen IV-derived biomimetic peptides, and to compositions for treating Tie2-related vascular permeability A composition of one or more collagen IV derived biomimetic peptides. Such peptides can promote the Tie2 agonist activity of angiopoietin 2 (Ang2), thereby stabilizing the vasculature and/or lymphatic vessels. |