http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110174386-B

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filingDate 2019-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110174386-B
titleOfInvention Host-guest sensor pair for detecting spermine and application thereof
abstract The invention discloses a sensing pair probe for detecting spermine in physiological environment, which comprises a main sulfonated cup [4]]Arene and guest 6,7,9,14 a-tetrahydropyrido [1,2-a ]]Pyrido [1'2'3'4']Imidazo [2,1-d]Pyrazine-5, 14-diimmonium (PMP) sensor pair, as follows: the sensor pair fluorescent probe researched by the invention can detect spermine and a main sulfonated cup [4] in a PBS (phosphate buffer solution)]The aromatic hydrocarbon and spermine can generate host-guest complexation, so that PMP dye molecules originally complexed in the guest are replaced, fluorescence is released, and the detection effect is achieved. The detection method is a fluorescence method, the detection speed is extremely high, and the fluorescence change is obvious. The spermine can be rapidly and efficiently detected in a physiological environment. The sensing pair serving as a novel fluorescent probe can be widely applied to the field of detection of tumor markers, and has a wide application prospect.
priorityDate 2019-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 38.