http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110172513-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b5c37a7251c558791f11ef3b78cdfeb1 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2019-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6ee232c62a769d771b171f250f66635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86746dff42a98d9bc988d34ea7dbd50c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d37d2380230c0c28ed2d020ffda611d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d03434c98e3c6bcd7ac91244b2c174e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e673ab2f05f93ba4676dd3b07cf9ea58 |
| publicationDate | 2019-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110172513-A |
| titleOfInvention | Screening method for clinical enrollment of mutant immune polypeptides |
| abstract | The present invention relates to a screening method for clinical enrollment of mutant immune polypeptides, performing whole-exome sequencing on normal tissues, performing whole-exome sequencing and whole-transcriptome sequencing on tumor tissues, and comparing the whole-body sequencing of tumor tissues and normal tissues. Exome sequencing results, and screening of mutant genes based on the whole transcriptome sequencing results of tumor tissues, translation of wild-type and screened mutant gene sequences and sequence comparison to synthesize immune polypeptides with corresponding amino acid sequences, and immune polypeptides Carry out in vitro detection of immunogenicity, and verify the killing effect of immune polypeptides on primary tumor cells, and screen to obtain immune polypeptides with immunogenicity and immune polypeptides with killing effects. |
| priorityDate | 2019-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 197.