http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110172081-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-50 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0062 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-227 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-52 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-52 |
| filingDate | 2019-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110172081-B |
| titleOfInvention | Polypeptide molecule derivative with mineralization function for biomedical tissue engineering and application thereof |
| abstract | The invention provides a polypeptide molecular derivative with mineralization function for biomedical tissue engineering and its application, belonging to the technical field of biomedical materials. The polypeptide molecule derivative has a general molecular structure formula of X-X-Cys-Cys-Cys-Cys-Y-Y-Z-W-NH 2 ; X is Asn or glucosylated asparagine; Y is Arg or Lys; Z is Glu or Asp; W is phosphorylated serine or phosphorylated threonine. The polypeptide molecular derivatives of the present invention can induce the oriented growth of apatite crystals, and synthesize biomaterials with a microstructure similar to the hard tissue of the body; they can self-assemble under the induction of calcium chloride to form 3D nano hydrogels, which can be applied to bone tissue Engineering scaffold materials, or applied to 3D in situ culture of cells; can be combined with collagen fibers to induce the mineralization of collagen fibers, so it can be applied to the study of bone tissue regeneration, as well as the induction of mineralization, regeneration and repair of cementum and dentin . |
| priorityDate | 2019-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.