http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110161099-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41e7550911d3e588caa3fbc6a252ad80 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-3278 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-327 |
| filingDate | 2019-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9090f79d8ecc7cacdd65bacc5e09f60a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2362326a152e361e27d7c79f0a8a214e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb271e6c3e0cfc65b37d27af9131e447 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b12a397262f670704436111107d8b59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a726891c1da07331a4cf678daa50e975 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13c75d145460789805e231580ec56ae5 |
| publicationDate | 2019-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110161099-A |
| titleOfInvention | Construction method of electrochemical aptamer sensor using titanium dioxide nanorod composite as electrochemical tracer |
| abstract | The invention relates to a construction method of an electrochemical aptamer sensor using a TiO 2 nanorod composite material as an electrochemical tracer: Pt-Sn bimetallic nanoparticles are uniformly deposited on cylindrical TiO 2 nanometer particles by an alcohol reduction method. PtSn@ TiO2 nanocomposites were synthesized on the surface of the rods. It was dispersed in the chitosan solution and dropped on the surface of the GCE electrode. BS 3 was used as a diamino cross-linking agent to immobilize the NH 2 ‑cDNA on the modified electrode surface, and then passed between the NH 2 ‑cDNA and the aptamer. The DNA hybridization immobilized the streptomycin aptamer on the electrode. When a mixture of streptomycin and exonuclease is introduced, the aptamer can preferentially bind specifically to streptomycin and separate from the NH 2 ‑cDNA on the electrode surface to form a single-stranded DNA structure. Exonuclease acting only on single-stranded DNA selectively digests and degrades single-stranded NH2 -cDNA, aptamer-streptomycin complex to release streptomycin, and the released streptomycin can be cyclically combined with The remaining aptamers on the electrode surface specifically bind. The electrochemical aptamer sensor can detect streptomycin rapidly and sensitively, with a large linear range and a low detection limit. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112444545-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112444545-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112903777-A |
| priorityDate | 2019-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.