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filingDate 2019-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de03c6cc7155aa429e7d9bbbfd41a7c7
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publicationDate 2019-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110157804-A
titleOfInvention Methylation sites, detection primers and kits for lung cancer diagnosis, curative effect prediction or prognosis
abstract The invention discloses a methylation site, a detection primer and a kit for lung cancer diagnosis, curative effect prediction or prognosis. The present invention provides 15 methylation sites for lung cancer diagnosis and curative effect prediction and 10 methylation sites for lung cancer prognosis, using a combination of one or more methylation sites as markers, through Measuring the change of the methylation level of the methylation site in the subject's blood sample can accurately diagnose early lung cancer and predict the efficacy or prognosis of lung cancer. The invention also provides specific detection primers and probes designed using these methylation sites as targets. The present invention further provides a kit for lung cancer diagnosis, prediction or prognosis constructed by using these primers and probes. The diagnosis, prediction or prognosis of lung cancer by using the kit of the invention has the advantages of strong specificity, strong sensitivity, high accuracy and the like.
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