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filingDate 2019-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110156601-B
titleOfInvention Method for preparing high-purity chlorogenic acid from stevia rebaudiana
abstract The invention discloses a method for preparing high-purity chlorogenic acid from stevia rebaudiana, belonging to the technical field of natural product chemistry. The invention takes stevia rebaudiana leaves as raw materials, water as an extraction medium, the leaching liquor is purified by polyamide resin or polyamide resin after being filtered and flocculated, water is used as an eluent, and the eluent is concentrated and crystallized to prepare a product with the chlorogenic acid mass content of more than 98%. Meanwhile, in the process of purifying chlorogenic acid by using resin, other collected components can be used for separating and extracting other stevia polyphenols and stevioside. In general, the method realizes the preparation of high-purity chlorogenic acid by taking stevia rebaudiana leaves as raw materials, the mass content of the chlorogenic acid in the product can reach more than 98 percent, the process operation is simple, organic solvents are hardly used, and the method is environment-friendly and safe.
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