| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78160fe5924d399deb065f8cbc5ad347 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-702
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-715 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-715
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-702 |
| filingDate |
2019-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9467b166a868990ef5f3b61005ba73e2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e44e8756071f08caa43aaae1344eb8e4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_258dd5139c78a7bc3f163d78048c4110
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_282b38d9b1dae1324fb13920d997227a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d58e45be5aa422c556f6a60a4c9d2aa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bee40211cc2efcb0daa87a8c09d6001 |
| publicationDate |
2019-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-110151773-A |
| titleOfInvention |
The application of oligomeric guluronic acid in the prevention and treatment of tauopathies |
| abstract |
The invention discloses oligomeric guluronic acid as an inhibitor of at least any one of total Tau protein expression, Tau protein hyperphosphorylation and endoplasmic reticulum stress activity and application in preparing medicine. The invention discloses that oligomeric guluronic acid has the functions of effectively inhibiting the expression level of total Tau, Tau protein phosphorylation and endoplasmic reticulum stress activity, thereby preventing the pathological process of tau protein disease. Uronic acid is non-toxic, so oligomeric guluronic acid can be used as an anti-tauopathic drug for the treatment of neurodegenerative diseases. |
| priorityDate |
2019-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |