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filingDate 2019-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac285a4c5346d189867c5f090389dded
publicationDate 2019-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110141556-A
titleOfInvention A kind of Abiraterone inclusion compound tablet and preparation method thereof
abstract The invention discloses an abiraterone inclusion compound tablet and a preparation method thereof, belonging to the technical field of pharmaceutical preparations. The tablet contains an abiraterone inclusion compound and pharmaceutical excipients. The preparation method comprises the following steps: adding abiraterone The clathrate, diluent and disintegrating agent are passed through a 80-mesh sieve, and mixed uniformly by an equal-volume incremental method; the binder is added to make a soft material, and the obtained soft material is passed through a 14-mesh sieve to make wet granules, and placed in an oven at 60°C Dry until the water content is 1-2%, pass through a 16-mesh sieve, weigh the weight of the dry granules; add 1% of the dry granule weight lubricant, mix evenly, and press into tablets; the present invention prepares the inclusion compound of abiraterone as Tablet, which has multiple advantages such as accurate dosage, stable quality, low cost, and convenient carrying, is the preferred dosage form of pharmaceutical preparations, and solves and improves the technical problems of compressibility and solubility of abiraterone tablets.
priorityDate 2019-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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