http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110134995-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cc4e13141d402ceb885f368dfa042348 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06F2119-08 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N15-0205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06F17-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N25-147 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06F30-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06F17-13 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F17-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F17-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F17-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N15-02 |
| filingDate | 2019-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c86e3efbe04a31eb7bb26d4f0029e42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bd065ee74c13d82421b72434066f441 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_737799d5a57ac02448b7fffeeb424ef3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d01fecd8b0f50de93b64c1c0512ffcc8 |
| publicationDate | 2019-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110134995-A |
| titleOfInvention | A method for on-line control of particle size distribution in dissolution and crystallization process |
| abstract | The invention discloses a method for on-line control of particle size distribution in the dissolution and crystallization process. In this method, the ATR probe is used to measure the current solute concentration on the anti-solvent crystallization online detection and control device, the FBRM probe is used to measure the current solute particle size distribution, and the constant temperature water bath is used to control the current temperature in the crystallization tank; the current measured solute concentration is used as a state variable, and the current The test temperature is used as an operating variable, and the process model is input, and the particle size distribution of the crystallization end point is obtained by solving the process model, and the objective function TARGET=||n(L,t f )‑n(L,t) s || 2 is minimized as the optimization goal , combined with the search range of the operating variable, the optimization equation is obtained; the temperature of the crystallization tank is adjusted according to the optimal cooling curve, so that the temperature in the crystallization tank coincides with the optimal cooling curve; the target value is set, and whether the crystallization end point is judged by the target value. The invention considers the non-negligible coalescence and fragmentation in the actual process, and solves the numerical discrete problem in the process of solving the coalescence and fragmentation items. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112485165-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112485165-B |
| priorityDate | 2019-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.