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filingDate 2019-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110129382-B
titleOfInvention Method for catalytic synthesis of chiral ortho-halogenated-alpha-phenylethyl alcohol by carbonyl reductase
abstract The invention discloses application of carbonyl reductase BaSDR1 or engineering bacteria containing carbonyl reductase BaSDR1 in asymmetric reduction of latent chiral ortho-halogenated acetophenone to preparation of chiral ortho-halogenated-alpha-phenylethyl alcohol; the structural general formula of the latent chiral ortho-halogenated acetophenone is shown as formula I: (I) (ii) a Wherein X is one of F, Cl and Br; r1 is hydrogen or halogen. Can synthesize chiral alcohol with high optical purity, is green, efficient and high in stereoselectivity.
priorityDate 2019-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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