http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110128666-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G81-00 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K103-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G81-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-06 |
| filingDate | 2019-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110128666-B |
| titleOfInvention | Functionalized polyethyleneimine coated nano-gold particle composite material and preparation method thereof |
| abstract | The invention relates to a functionalized polyethyleneimine coated gold nanoparticle composite material and a preparation method thereof 2 - (mPEG), adding MAL-PEG-SVA solution, and reacting to obtain PEI 2 - (PEG-MAL) - (mPEG), then adding chelating agent DTA and fluorescent marker FI in sequence, and then adding chloroauric acid and NaBH 4 To obtain { (Au) 0 ) 200 ‑PEI.NH 2 -FI-DTA- (PEG-MAL) - (mPEG) } PENPs, followed by APAS, followed by acetylation to give { (Au) 0 ) 200 NHAc-FI-DTA- (PEG-APAS) - (mPEG) } PENPs, and finally radionuclides 99m And (4) marking Tc on the chelating agent DTA to obtain the product. The functionalized polyethyleneimine coated nano-gold particles prepared by the invention can improve the uptake of cancer cells to the cancer cells, can be used as a good SPECT/CT imaging nano-contrast agent, and has potential application value in the aspect of multi-modal tumor imaging. |
| priorityDate | 2019-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 102.