http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110128588-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F220-302 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F220-34 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F220-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-785 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-785 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-02 |
| filingDate | 2019-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110128588-B |
| titleOfInvention | Temperature-sensitive bacteriostatic cationic dendrimer and preparation method thereof |
| abstract | The invention relates to a temperature-sensitive bacteriostatic cationic dendrimer and a preparation method thereof. The structural formula of the polymer is as follows: (ii) a The invention adopts dendritic alkoxy ether as a temperature-sensitive element and takes guanidinated cation as an identification element. The temperature sensitivity and good biocompatibility of the alkoxy ether dendronization element are utilized to endow the polymer with temperature responsiveness and reduce the biotoxicity; and the guanidino has higher selectivity on bacterial cell membranes and no toxicity on mammalian cells, and enhances the capability of the guanidino in inducing the bacterial cell death caused by membrane permeation. Meanwhile, the recycling function can be realized by changing the temperature, so that the use cost is reduced. The invention aims to realize inhibition of the bacterial growth process and develop a recyclable type by a temperature difference methodThe bacteriostatic agent provides wide prospect. |
| priorityDate | 2019-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.