http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110128452-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2018-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110128452-B |
titleOfInvention | Gold complex and synthesis method and application thereof |
abstract | The invention discloses a gold complex and a synthesis method and application thereof. The synthesis method of the gold complex comprises the following steps: placing chloroauric acid tetrahydrate or chloroauric acid salt and phenethylamine ligand in an organic solvent, coordinating under the condition of keeping out of the sun, cooling the reactant, standing for crystallization, and collecting crystals to obtain the chlorauric acid tetrahydrate or chloroauric acid salt and phenethylamine ligand; wherein the chloraurate is sodium or potassium chloraurate, and the phenylethylamine ligand is piperonylethylamine. Experiments of the applicant show that the complex has good proliferation inhibition activity and drug resistance to certain tumor cell strains, has low toxicity to human normal cells HL-7702, and also has high physiological stability. The complex structure of the invention is shown as the following formula (I): |
priorityDate | 2018-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.