http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110128268-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_215fd62f148bc5aab2bfc8e46ecd6126 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f948edf5aaba56ec3ad666c2572fdd1f |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 |
filingDate | 2019-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2af65a1c6853cf0f6cfbb23de6b3822c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a597260cd0c6e6aee4865c123eb6387e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1f73ef93ecd74baa3b3bf410e7f8f50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36d66aebed87e01fb9c3df3ab8d87e2d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5782af202bc43b4db5c5c61709cff0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0965a48d2e07d8311749e0ef4afec57a |
publicationDate | 2019-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110128268-A |
titleOfInvention | A kind of method of continuous production ibuprofen ester |
abstract | The present invention relates to a kind of methods of continuous production ibuprofen ester, belong to field of medicine and chemical technology;Include the following steps;One, the washing ketal that condensation reaction generates, by being pumped into level-one rearrangement reactor, catalyst squeezes into level-one rearrangement reactor by pumping, and the laggard rearrangement reaction of solvent is added;Two, rearrangement reaction successively carries out in multiple concatenated continuous rearrangement reactors, and reaction of high order is overflow discharging;Three, the gas phase of reaction of high order enters condenser, and condensed material enters return tank;The process that the solvent having more enters condensation reaction from return tank side overflow.Four, rearrangement solution is discharged by afterbody rearrangement reactor overflow, into subsequent processing;The reaction time is shortened, the generation of rearrangement process side reaction is reduced, the yield of ibuprofen ester is improved to 95% or more. |
priorityDate | 2019-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.