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filingDate 2019-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110123832-B
titleOfInvention Ophthalmic composition containing non-drug-resistant bactericide
abstract An ophthalmic composition comprising a non-drug resistant biocide, an aqueous solution of which comprises at least 1ppm to 10ppm polyhexamethylene monoguanidine having a relative molecular weight of 1000kDa to 5000 kDa. Effective amounts of germicidal sterilant, surfactants, buffers, viscosity builders, tonicity adjusting agents, chelating agents and other active ingredients may also be included. The composition of the invention adopts polyhexamethylene guanidine with high polymerization degree as an antimicrobial active component, can overcome the drug resistance of the traditional antimicrobial component known by technicians in the field to bacteria, exerts broad-spectrum and efficient antimicrobial preservative effect, and can continuously maintain the sterile state of the multi-dose composition for a long time, thereby ensuring the health and safety of users.
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