http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110123799-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-167 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-167 |
filingDate | 2018-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110123799-B |
titleOfInvention | Application of rafoxanide in preparation of antitumor drugs |
abstract | The invention provides a new application of a commonly used insecticide rafoxanide in preparing antitumor drugs. The invention discovers that rafoxanide has obvious inhibition effect on p38MAPK, and can obviously inhibit the proliferation of myeloma, lymphoma, liver cancer, breast cancer, lung cancer and prostate cancer cells. In addition, at 15mg/kg, rafoxanide can obviously inhibit the growth of human myeloma cell H929 nude mouse transplantation tumor, has no influence on the body weight of nude mice, and has good application prospect. |
priorityDate | 2018-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.