http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110117631-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_653c418e41edbb4e1ce8bc5e53e70cec |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K9-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K9-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 |
| filingDate | 2019-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ce7192a25595df2280faf2650bba625 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b4c47a5638017a89114566c1c5faa04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df2b1934d13c8e2e9ee0b5fa532d24b5 |
| publicationDate | 2019-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110117631-A |
| titleOfInvention | A method for preparing Globotriose-linked active glycopeptides using three glycosyltransferases |
| abstract | The invention discloses a method for preparing active glycopeptides containing Globotriose-linked by using three glycosyltransferase step-by-step synthesis methods. Firstly, UDP-Glc is transferred to N-X(X) by using N-glycosyltransferase ApNGT ≠P)‑T/S glycosylation site on the Asn amino acid residue on the polypeptide, then synthesize Peptide‑Lactose under the action of β‑1,4‑galactosyltransferase LgtB, and then in α‑1, The product is synthesized under the action of 4-galactosyltransferase LgtC, and then purified by high-pressure liquid chromatography, the eluted sample is concentrated, and the biologically active Peptide-globotriose active glycopeptide is obtained after the product is freeze-dried. The method of the invention provides the possibility for mass and rapid production of various Globotriose-based oligosaccharide peptides, and has broad application prospects. |
| priorityDate | 2019-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.