| abstract |
The invention relates to an N 1 , N 3 -disubstituted imidazole type ionic liquid as a solvent, NH-sulfinyl imide as a raw material, a diazo compound, an alkyne and a sulfur ylide as a coupling reagent, and a transition metal catalyzed C-H A new green synthesis method for mild and efficient synthesis of 1,2-benzothiazine derivatives by activation/cyclization reaction. Compared with other technologies, the invention has milder conditions, simple operation, safety and environmental friendliness; high catalytic activity, high reaction yield, and wide application range of substrates; the solvent and catalyst can be recycled, and the reaction cost is reduced. |