http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110088092-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-28 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184 |
filingDate | 2017-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110088092-B |
titleOfInvention | Compounds, methods of preparation, pharmaceutical compositions, uses of compounds and methods of treating mental disorders and/or sleep disorders |
abstract | The present invention relates to novel and inventive pharmacologically active benzimidazole derivative compounds with surprisingly high affinity for melatonin MT1 and MT2 receptors and low affinity for CYP450 complex enzymes, especially CYP1A2. In addition to methods of making the compositions, the present invention also relates to novel and inventive synthetic routes to these compounds, pharmaceutical compositions comprising the compounds and the use of these compounds in the treatment of mental disorders and/or sleep associated with these receptors Use in individuals affected by disorders, in particular depression, anxiety, circadian cycle disorders. |
priorityDate | 2016-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 563.